Ultimately, the IBM EBO approach resulted in a number of new multi-billion dollar businesses and re-energised and re-established IBM as a major player in the IT space. 
Investigators considering applying to the NCCIH for a clinical trial award should refer to the NCCIH Clinical Trials Policy web site . Information about NCCIH Policies, Guidelines and Sample Templates for Clinical Trials at: http:///Funding/Clinical_Research/NCCIH_ . Investigators are encouraged to review the NCCIH Clinical Research Toolbox ( http:///grants/toolbox ) to learn more about NCCIH's requirements for clinical research and NCCIH’s policy on natural product integrity ( http:///research/policies/ ).
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While these principles have been common practice in sectors such as energy and aerospace for well over a decade, they are relatively new to construction. Should it become the process of choice though, we believe it will transform our industry – for good.